The latest issue of The CLER Review (Vol. 18, Issue 2) is now available.

This issue provides Additional Data and Commentary examining the available science regarding the European Commission (EC) ‎proposal to apply a mixture assessment factor, also called a mixture allocation factor (MAF) to ‎every chemical requiring a quantitative risk evaluation in the REACH Chemicals Regulation ‎database.

The data assessment does not support the proposed ‎application of the MAF to every chemical in the REACH database. Instead, the available data indicate that industrial ‎chemicals in the REACH registration database should not be the only focus to identify those few ‎chemicals which contribute to environmental mixture risk.‎

The data assessment in this issue, and the commentary and the supporting studies in Vol. 18, Issue 1 provide a strong case that a MAF value should be applied in a more focused assessment rather than to every chemical in the REACH database.

Volume 18, Issue 1 and Volumes 15-17 of The CLER Review are also available for download below. For copies of volumes 1 – 14, please email

The purpose of The CLER Review is to bring together in one publication the latest scientific research and public policy information on linear alkylbenzene sulfonate (LAS) and its precursor, linear alkylbenzene (LAB). LAS is one of the most widely used – and widely studied – chemicals worldwide.

Viewing instructions:

  • To view the full cover page, click on the magnifying glass icon.
  • To view the table of contents and preface, click on the arrow icon. To download the entire issue, click on the link at the bottom of the page.